In a relatively short period of time, an impressive 40 percent of these companies are already
generating revenues. Israel’s entrepreneurial ecosystem creates opportunities for start-ups to
become advanced, commercially viable and
promising businesses. As proof of the industry’s development, 2014 life science exports reached $8.5 billion,
growing steadily since 2008; while a rich pipeline of seed companies promises to perpetuate current growth.
The Israeli booth in the exhibition presents more than 60 companies focusing on the treatment of chronic diseases,
digital medicine, healthy aging and rehabilitation equipment, in fact the largest medical equipment and
medical equipment exhibition in the world.

The Largest Sector is Medical Devices and HealthCare IT Technologies (more than 65 percent
of companies). In the medical device arena, Israeli scientists and engineers have integrated
advanced technologies in electronics, communications and electro-optics to develop
world-class innovations in Digital Imaging, Medical Lasers,
Telemedicine, Early Diagnostic and Smart Surgical equipment and more. More than 500 medical device
exporters engaged in a variety of medical applications such as Cardiovascular and Peripheral Vascular,
Neurology and Degenerative Diseases, Emergency Medicine,
Intensive Care and Rehabilitation, Respiratory and Airway Management, Oncology, Women’s Health,
Orthopedics and Sport Medicine, Gastrointestinal, Infection Control, Ophthalmology, Pain and Wound
Management, Oral and Dental, Dermatology and Aesthetics.

There is no other country in the world with such a concentration of life science companies. Companies
rooted in top international academic and research institutions; staffed by highly educated and skilled teams;
operating within an entrepreneurial and audacious climate, to offer a variety of innovative medical solutions
and technologies that answer today’s healthcare challenges:
to lower overall healthcare costs and meet the world’s evolving needs of aging populations while creating
significant investor value.

Among many of very interesting company we find ALLIUM MEDICAL which Advanced Minimally Invasive
Products includes 4 distinct product lines: Cardiovascular, Urology and Continence Care, Uro-Gynecology
and Pelvic Reconstruction and Gastroenterology.
The company offers long term, fully covered, expandable and retrievable metal stents. The Allium stents
are anatomically and functionally compatible to specific organs for the treatment of obstructions in the
urinary and GI tracts, offers physicians and patients highly effective stenting solutions for significantly
enhancing clinical results and patients’ quality of life.
The firm has developed a proprietary stent technology platform to expedite the development of site-specific
stents. Each Allium stent is designed specifically to match the site to be treated and the surrounding anatomy.
This proprietary technological platform allows Allium to produce thin walled, entirely covered stents with
a large lumen, but with the critical advantage of removability.

Other Israeli company that raised interested visitors called B-Cure Laser Pro- Diabetic Foot Ulcers-
NEW outstanding Double blind CLINICAL TRIAL RESULTS.  In fact it is the world’s first portable Evidence
base Low Level Laser Therapy (LLLT) medical device with the Healing Power of a clinic: For treating efficiently
hard to heal wounds, Orthopedic conditions, and to alleviate pain. The goal is to bring innovation in treatment,
medical care, and quality of life.
New double blind clinical trials for both wound healing and orthopedic conditions support the efficacy.
Diabetic Foot Ulcer CLINICAL TRIAL- results: The treatment method is also significantly effective to treat
pressure wounds, cuts, burns, and post operation wounds.

We find also Biop Medical is an Israeli medical device startup, which has developed an innovative technology
for the identification of cancerous cells in epithelium tissues. The technology is a platform technology, which will
be implemented in a number of devices for cancer screening and diagnosis, beginning with cervical cancer.
Cervical cancer is the second most common cancer among women worldwide.
Biop’s real-time screening tool offers standard colposcope capabilities with state-of-the-art, enhanced features.
The novel device combines advanced, high-resolution optics with integrated micro and macro cameras and other
optical elements to produce highly sensitive optical signatures for automatic identification of suspicious areas
and quantification of the cancer stage. The collected data is combined and analyzed using Biop’s
proprietary algorithm. Preliminary commercialization of Biop’s proprietary transducer will
replace current colposcopy and other
existing cervical screening technologies.

Further company that we saw at the Medica, Lumenis  the world’s largest energy-based medical device
company for surgical, ophthalmology and aesthetic solutions. As an international leader in the development
and commercialization of innovative energy-based technologies, including laser, Intense Pulsed Light
(IPL), Radio-Frequency (RF) and Ultrasound, Lumenis has redefined medical treatments and set numerous
technological and clinical gold standards.

Lumenis’ vision is to provide better technology for better patient care through innovative energy-based
solutions. With a ground-breaking technological legacy of more than 50 years, we are committed to enhancing
patient health and quality of life; addressing new and growing needs of aging populations; and offering
medical professionals innovative solutions to meet the developing and dynamic healthcare
environment of the 21st century.

Lumenis operates in three core markets: Surgical, Ophthalmology and Aesthetics. Throughout the history,
Lumenis has created innovative solutions for previously untreatable conditions and designed advanced
technologies that have revolutionized existing treatment methods in each and every one of
the sectors we operate in.

8.11.2021